Bromelain improved cognitive & mood behaviors, oxido-inflammatory indices and cholinergic transmission in scopolamine-induced neurotoxicity in male wistar rats – PubMed Black Hawk Supplements
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Alzheimer’s disease (AD) is associated with pathophysiological and psychological disturbances including cognitive decline, depression, anxiety and motor imbalance. Conventional drugs for managing AD do not address associated non-neurocognitive co-morbidities, hence the need to investigate alternative therapies especially from plants. The neuroprotective benefits of bromelain have been identified, but its impacts on scopolamine-induced neurotoxicity is yet to be elucidated. Twenty-Five male rats…
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Hartinger SM, Palmeiro-Silva YK, Llerena-Cayo C, Blanco-Villafuerte L, Escobar LE, Diaz A, Sarmiento JH, Lescano AG, Melo O, Rojas-Rueda D, Takahashi B, Callaghan M, Chesini F, Dasgupta S, Posse CG, Gouveia N, Martins de Carvalho A, Miranda-Chacón Z, Mohajeri N, Pantoja C, Robinson EJZ, Salas MF, Santiago R, Sauma E, Santos-Vega M, Scamman D, Sergeeva M, Souza de Camargo T, Sorensen C, Umaña JD, Yglesias-González M, Walawender M, Buss D, Romanello M. Hartinger SM, et al. Lancet Reg Health Am. 2024 Apr 23;33:100746. doi: 10.1016/j.lana.2024.100746. eCollection 2024 May. Lancet Reg Health Am. 2024. PMID: 38800647 Free PMC article. Review.
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