Dietary Effect of Withania somnifera Root Powder on Growth, Hematobiochemical Parameters, Immunity, and Disease Resistance to Aeromonas hydrophila in Cyprinus carpio – PubMed Black Hawk Supplements

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This study investigates the influence of Withania somnifera root powder (WSRP) on different aspects of common carp (Cyprinus carpio), including growth, hematobiochemical parameters, antioxidant status, nonspecific immune response, and resilience to bacterial infections. Over a 60-day period, 180 common carp fingerlings (11.73 ± 0.52 g) were subjected to diets supplemented with increasing WSRP levels (0 (control), 1% (WSRP1), 2.5% (WSRP2.5), and 4% (WSRP4)). Nonspecific immune parameters were…
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Dietary Effect of Withania somnifera Root Powder on Growth, Hematobiochemical Parameters, Immunity, and Disease Resistance to Aeromonas hydrophila in Cyprinus carpio - PubMed

Dietary Effect of Withania somnifera Root Powder on Growth, Hematobiochemical Parameters, Immunity, and Disease Resistance to Aeromonas hydrophila in Cyprinus carpio

Syed Sikandar Habib et al. Aquac Nutr. .

Abstract

This study investigates the influence of Withania somnifera root powder (WSRP) on different aspects of common carp (Cyprinus carpio), including growth, hematobiochemical parameters, antioxidant status, nonspecific immune response, and resilience to bacterial infections. Over a 60-day period, 180 common carp fingerlings (11.73 ± 0.52 g) were subjected to diets supplemented with increasing WSRP levels (0 (control), 1% (WSRP1), 2.5% (WSRP2.5), and 4% (WSRP4)). Nonspecific immune parameters were evaluated using serum samples collected at intervals of 0, 20, 40, and 60 days. After the feeding trial, the fish underwent experimental challenge with Aeromonas hydrophila, and relative percentage survival (RPS) was monitored for 14 days. The findings revealed a considerable (p < 0.05) enhancement in growth performance and a decreased feed conversion ratio (FCR) with increasing WSRP supplementation. Additionally, hematological and biochemical profiles exhibited improvements in groups receiving WSRP-enriched diets. Fish serum antioxidant status showed a significant (p < 0.05) increase, as indicated by increased activities of total antioxidant capacity (TAC), superoxide dismutase (SOD), catalase (CAT), and reduced glutathione (GSH) in WSRP4. WSRP-supplemented diets led to remarkable enhancements in lysozyme activity (p = 0.001), phagocytic activity (p = 0.002), and RPS (p = 0.003), peaking in WSRP4 at day 60. Furthermore, WSRP2.5 and WSRP4 demonstrated a substantial decrease (p > 0.05) in serum glucose and cortisol levels compared to other groups. In conclusion, WSRP proves valuable for enhancing growth, blood parameters, antioxidant balance, immune response, and infection resistance in common carp, especially at 2.5%-4% dietary supplementation levels. In the future, it will be crucial to study the long-term effects of WSRP supplementation on fish health, as well as its potential for large-scale aquaculture and economic viability in the aquafeed industry.

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Conflict of interest statement

The authors declare there is no conflict of interest about this article.

Figures

Figure 1
Figure 1

Effects of various concentrations of W. somnifera root powder (WSRP) on serum lysozyme activity of C. carpio. Different letters indicate significant difference among the groups.

Figure 2
Figure 2

Effects of various concentrations of W. somnifera root powder (WSRP) on phagocytic activity of C. carpio. Different letters indicate significant difference among the groups.

Figure 3
Figure 3

Effects of various concentrations of W. somnifera root powder (WSRP) on relative percentage survival of C. carpio. Different letters indicate significant difference among the groups.

References

    1. Pradeepkiran J. A. Aquaculture role in global food security with nutritional value: a review. Translational Animal Science . 2019;3(2):903–910. – PMC – PubMed
    1. Laltlanmawia C., Saha R. K., Saha H., Biswas P. Ameliorating effects of dietary mixture of Withania somnifera root extract and vitamin C in Labeo rohita against low pH and waterborne iron stresses. Fish & Shellfish Immunology . 2019;88:170–178. – PubMed
    1. Yousefi M., Ghafarifarsani H., Hoseinifar S. H., Rashidian G., Van Doan H. Effects of dietary marjoram, Origanum majorana extract on growth performance, hematological, antioxidant, humoral and mucosal immune responses, and resistance of common carp, Cyprinus carpio against Aeromonas hydrophila. Fish & Shellfish Immunology . 2021;108:127–133. doi: 10.1016/j.fsi.2020.11.019. – DOI – PubMed
    1. Shekarabi S. P. H., Omidi A. H., Dawood M. A., Adel M., Avazeh A., Heidari F. Effect of black mulberry (Morus nigra) powder on growth performance, biochemical parameters, blood carotenoid concentration, and fillet color of rainbow trout. Annals of Animal Science . 2020;20(1):125–136.
    1. Latif M., Faheem M., Asmatullah, Hoseinifar S. H., Van Doan H. Dietary black seed effects on growth performance, proximate composition, antioxidant and histo-biochemical parameters of a culturable fish, rohu (Labeo rohita) Animals . 2020;11(1)48 – PMC – PubMed

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Dietary Effect of Withania somnifera Root Powder on Growth, Hematobiochemical Parameters, Immunity, and Disease Resistance to Aeromonas hydrophila in Cyprinus carpio – PubMed